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# Anecrit's Newsletter #00
- URL: https://www.anecrit.com/newsletter-0029052025/
- Published: 2025-05-29T11:12:03.000Z
- Updated: 2025-08-24T14:55:55.000Z
- Author: BENHALIMA Othmane
- Tags: Newsletter

**Issue #\[00\] | \[13 - 28/05/2025\]**

### **Welcome!**

Hey there! Welcome to the very first issue of **Anecrit's newsletter**.

Can you guess how many papers were published across relevant journals in anesthesiology and critical care medicine recently? Try, over **400 papers**! That's an insane amount of literature for any clinician trying to stay updated, right? I think this newsletter solves a problem we all share: too little time.

This inaugural issue isn't perfect, and it might not cover every relevant paper you'd hoped for. But please remember, this is **our newsletter**. It will change and evolve over time to become a resource for all of us. So, please don't hesitate to share your **feedback and suggestions**. We're building this together!

### **Featured Articles :**

Have you read the OPTPRESS trial?

Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial, Intensive care medicine, 13 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07910-4)

I'll be publishing a summary and an analysis of this trial tomorrow, stay tuned for it.

# **Anesthesiology Highlights**

### **I. Guidelines & Consensus Statements :**

1. Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement, British Journal of Anaesthesia, In Press 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900214-4/abstract).

### **II. Systematic Reviews & Meta-Analyses :**

1. Efficacy of Epidural Analgesia Compared to Intravenous Lidocaine for Postoperative Pain in Major Abdominal Surgery: A Systematic Review and Meta-Analysis, Current Anesthesiology Reports, 13 May 2025, [Link](https://link.springer.com/article/10.1007/s40140-025-00699-4).
2. Temporal Trends and Severity of Postoperative Delirium in Cardiac Surgery: Insights from A Systematic Review and Meta-Analysis, Journal of Cardiothoracic and Vascular Anesthesia, 17 May 2025, [Link](https://www.jcvaonline.com/article/S1053-0770%2825%2900402-1/abstract).
3. The Protective Effect of Remote Ischemic Preconditioning on Acute Kidney Injury Following Pediatric Cardiac Surgery: A Systematic Review and Meta-Analysis, Journal of Cardiothoracic and Vascular Anesthesia, 17 may 2025, [Link](https://www.jcvaonline.com/article/S1053-0770%2825%2900403-3/abstract)
4. Effect of dexmedetomidine on the incidence of postoperative delirium following major cardiac surgery: An updated meta-analysis, Journal of Cardiothoracic and Vascular Anesthesia, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004355).

### **III .Randomized Controlled Trials (RCTs) :**

1. Intravenous dexmedetomidine as addition to dexamethasone adjunct for interscalene brachial plexus block for postoperative analgesia after arthroscopic shoulder surgery: A randomised, double-blinded, single centre trial, European Journal of Anaesthesiology, May 14 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/intravenous%5Fdexmedetomidine%5Fas%5Faddition%5Fto.296.aspx).
2. Impact of Erythromycin and Metoclopramide on Gastric Emptying of Solids in Term Pregnant Women Scheduled for Elective Cesarean Delivery: A Randomized Controlled Trial, Anaesthesia Critical Care & Pain Medicine, 14 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000761?via%3Dihub).
3. Repeat-dose dexamethasone to prevent pain relapse after total knee arthroplasty in high-pain-response patients: A randomised, double-blind, placebo-controlled superiority trial, European Journal of Anaesthesiology, May 14 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/repeat%5Fdose%5Fdexamethasone%5Fto%5Fprevent%5Fpain%5Frelapse.297.aspx).
4. Multimodal prehabilitation before lung resection surgery: a multicentre randomised controlled trial, British Journal of Anaesthesia, 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900196-5/fulltext).
5. Effect of Dinalbuphine sebacate on postoperative multimodal analgesic strategy in video-assisted thoracoscopic surgery: a double-blind randomized controlled trial, BMC Anesthesiology, 17 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03118-7).
6. Interleukin-1 receptor antagonist polymorphisms in women receiving epidural analgesia who develop maternal intrapartum fever: a prospective, multicentre Mendelian randomised study, British Journal of Anaesthesia, 14 May 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900226-0/fulltext).
7. Low-dose Esketamine combined with Propofol in microscopic pediatric strabismus surgery: a randomized controlled study, BMC Anesthesiology, 14 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03095-x).
8. Effects of an opioid-free care pathway vs. opioid-based standard care on postoperative pain and postoperative quality of recovery after laparoscopic bariatric surgery: A multicentre randomised controlled trial, European Journal of Anaesthesiology, May 15 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/effects%5Fof%5Fan%5Fopioid%5Ffree%5Fcare%5Fpathway%5Fvs%5F.298.aspx).
9. Safety of remimazolam in deep sedation during flexible fiberoptic bronchoscopy: a prospective, randomized controlled trial, BMC Anesthesiology, 15 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03117-8).
10. Effects of a national team training intervention for operating theatre teams on patient and staff outcomes: a stepped-wedge cluster-randomised trial and mixed-methods study, British Journal of Anaesthesia, In Press 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900230-2/fulltext?dgcid=raven%5Fjbs%5Faip%5Femail).
11. Ultrasound-guided supraclavicular brachial plexus block as an additive to sevoflurane anesthesia in pediatrics undergoing brachiobasilic arteriovenous fistula operation: randomized controlled clinical trial, BMC Anesthesiology, 16 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03091-1).
12. Sugammadex or neostigmine for reversal of neuromuscular block on the quality of postoperative recovery in elderly adults undergoing video-assisted thoracoscopic lobectomy: a randomised controlled trial, BMC Anesthesiology, 16 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03128-5).
13. Effects of different doses of remifentanil combined with sevoflurane anesthesia on postoperative analgesia and hemodynamics in pediatric patients undergoing laparoscopic inguinal hernia repair, BMC Anesthesiology, 15 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03104-z).
14. A novel approach to ultrasound-guided L3-4 thoracolumbar fascia injection for chronic pain after spine surgery: a prospective pilot study, BMC Anesthesiology, 15 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03046-6).
15. Methylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial, Critical Care Medicine, May 21 2025, [Link](https://journals.lww.com/ccmjournal/fulltext/9900/methylprednisolone%5Ffor%5Finfant%5Fheart%5Fsurgery%5F.527.aspx).
16. Ultrasound Gel versus Saline for Acoustic Coupling in Ultrasound-Guided Regional Anesthesia: A Randomized, Cross-Over, Simulation Study, Anesthesia & Analgesia, May 26, 2025, [Link](https://journals.lww.com/anesthesia-analgesia/fulltext/9900/ultrasound%5Fgel%5Fversus%5Fsaline%5Ffor%5Facoustic%5Fcoupling.1312.aspx).
17. A Randomized Clinical Trial of Dexmedetomidine on Delirium, Cognitive Dysfunction, and Sleep After Non-Ambulatory Orthopedic Surgery With Regional Anesthesia, Anesthesia & Analgesia, May 22, 2025, [Link](https://journals.lww.com/anesthesia-analgesia/fulltext/9900/a%5Frandomized%5Fclinical%5Ftrial%5Fof%5Fdexmedetomidine%5Fon.1303.aspx).
18. Thoracic paravertebral block versus local infiltration anesthesia for percutaneous kyphoplasty to treat osteoporotic vertebral compression fractures combined with intercostal neuralgia: a randomized controlled trial, BMC Anesthesiology, 19 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03114-x).
19. Chewing gum on postoperative oral Malodor in patients undergoing general anesthesia: a randomized non-inferiority trial, BMC Anesthesiology, 21 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03134-7#).
20. Comparison between upper body and full underbody forced-air warming blanket in pediatric patients undergoing cardiovascular interventions under general anesthesia: a randomized controlled trial, BMC Anesthesiology, 21 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03100-3#).
21. No effect of tetracosactide for treatment of postdural puncture headaches in parturient women: a double-blind randomised controlled clinical trial, British Journal of Anaesthesia, 20 May 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900233-8/fulltext).
22. PeRiOperative Glucose PRAgMatic (PROGRAM): a randomized trial of standardized insulin management in surgical patients, Anesthesiology, 23 May 2025, [Link](https://journals.lww.com/anesthesiology/abstract/9900/perioperative%5Fglucose%5Fpragmatic%5F%5Fprogram%5F%5F%5Fa.689.aspx).
23. Self-directed learning versus traditional instructor-led learning for education on a new anaesthesia workstation: a noninferiority, randomised, controlled trial, British Journal of Anaesthesia, 23 May 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900276-4/fulltext).
24. Double dural puncture epidural improves quality of labour analgesia without increasing adverse effects in primipara: A randomised controlled trial, European Journal of Anaesthesiology, 22 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/double%5Fdural%5Fpuncture%5Fepidural%5Fimproves%5Fquality%5Fof.303.aspx).
25. QUAdratus lumborum block in caesarean section (QUALICS) study: A randomised clinical trial comparing intrathecal morphine, quadratus lumborum block and the combination of both for postoperative analgesia in caesarean sections, European Journal of Anaesthesiology, 22 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/quadratus%5Flumborum%5Fblock%5Fin%5Fcaesarean%5Fsection.304.aspx).
26. Recovery from deep neuromuscular blockade using different sugammadex doses in elderly patients undergoing laparoscopic robot-assisted prostatectomy: A prospective, randomised, double-blind, phase III trial, European Journal of Anaesthesiology, 22 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/recovery%5Ffrom%5Fdeep%5Fneuromuscular%5Fblockade%5Fusing.301.aspx).
27. Postoperative Analgesia Effect Evaluation of Perineural Dexamethasone Plus Various Doses of Ropivacaine in Interscalene Brachial Plexus Block: A Randomized Controlled Trial, The Clinical Journal of Pain, 22 May 2025, [Link](https://journals.lww.com/clinicalpain/fulltext/9900/postoperative%5Fanalgesia%5Feffect%5Fevaluation%5Fof.261.aspx).
28. Comparison between transtracheal and intravenous 2% lignocaine in attenuating hemodynamic stress response following direct laryngoscopy and endotracheal intubation: a randomized controlled trial, BMC Anesthesiology, 24 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03102-1).
29. Comparison of analgesic efficacy of erector spinae plane block at different levels in laparoscopic cholecystectomies: a randomized controlled trial, BMC Anesthesiology, 26 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03138-3) .

### **IV. Reviews:**

1. Pharmacokinetics and Pharmacodynamics of Analgesic and Anesthetic Drugs in Patients During Cardiac Surgery With Cardiopulmonary Bypass: A Narrative Review, Anesthesia & Analgesia, 16 May 2025, [Link](https://journals.lww.com/anesthesia-analgesia/fulltext/9900/pharmacokinetics%5Fand%5Fpharmacodynamics%5Fof%5Fanalgesic.1299.aspx).
2. Anaesthesia for resection of vestibular schwannoma, BJA Education, May 14, 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900026-5/fulltext?dgcid=raven%5Fjbs%5Faip%5Femail).
3. Hyperangulated videolaryngoscopy, BJA Education, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900023-X/fulltext).
4. Adjuncts for neuraxial anaesthesia in obstetrics, BJA Education, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900022-8/fulltext).
5. Perioperative management of tracheo-oesophageal fistula and oesophageal atresia, BJA Education, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900025-3/fulltext).
6. Pathophysiology and risk factors for postoperative nausea and vomiting in adults and children, BJA Education, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900024-1/fulltext).
7. Sublingual ketamine for acute postoperative pain: an emerging addition to multimodal analgesia, British Journal of Anaesthesia, In Press 2025, [Link](https://click.notification.elsevier.com/CL0/https:%2F%2Fwww.bjanaesthesia.org%2Farticle%2FS0007-0912%2825%2900232-6%2Ffulltext%3Fdgcid=raven%5Fjbs%5Faip%5Femail/1/01000196ddc6b16d-1a8131c5-3691-4f7f-9b71-cf2e1e379ddd-000000/ae3zvrS23gVhaUQ4gjiPLd6mzpjss9G3Od-nHlaRZHw=405).
8. Right Ventricular Function and Echocardiographic Pressure-Volume Loops; Overview and Perioperative Clinical Implications, Journal of Cardiothoracic and Vascular Anesthesia, 17 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S105307702500401X).
9. Perioperative ventilation support, what clinicians and searchers must know, Anaesthesia Critical Care & Pain Medicine, 22 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000864).
10. Sugammadex Anaphylaxis: Mechanisms, Diagnosis, and Incidence, Anesthesiology, 20 May 2025, [Link](https://journals.lww.com/anesthesiology/citation/9900/sugammadex%5Fanaphylaxis%5F%5Fmechanisms,%5Fdiagnosis,%5Fand.686.aspx).
11. Anaesthesia for clipping of intracranial aneurysms, BJA Education, 24 May 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900038-1/abstract).
12. Regional anesthesia in bariatric surgery, Current Opinion in Anesthesiology, 29 April 2025, [Link](https://journals.lww.com/co-anesthesiology/fulltext/9900/regional%5Fanesthesia%5Fin%5Fbariatric%5Fsurgery.303.aspx).
13. The future of target-controlled infusion and new pharmacokinetic models, Current Opinion in Anesthesiology, 26 May 2025, [Link](https://journals.lww.com/co-anesthesiology/fulltext/9900/the%5Ffuture%5Fof%5Ftarget%5Fcontrolled%5Finfusion%5Fand%5Fnew.306.aspx).
14. Advancing electroencephalography education in anesthesiology, Current Opinion in Anesthesiology, 26 May 2025, [Link](https://journals.lww.com/co-anesthesiology/fulltext/9900/advancing%5Felectroencephalography%5Feducation%5Fin.304.aspx).
15. Remimazolam for anesthesia in cardiac and noncardiac surgery. A narrative literature review and synthesis, Anaesthesia Critical Care & Pain Medicine, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000876).

## By topic:

#### By topic:

1. ****General:**

****Guidelines & Consensus Statements:**

- Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement, **British Journal of Anaesthesia*, In Press 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900214-4/abstract).

****Randomized Controlled Trials (RCTs):**

- Multimodal prehabilitation before lung resection surgery: a multicentre randomised controlled trial, **British Journal of Anaesthesia*, 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900196-5/fulltext).
- Chewing gum on postoperative oral Malodor in patients undergoing general anesthesia: a randomized non-inferiority trial, **BMC Anesthesiology*, 21 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03134-7#).
- Effects of a national team training intervention for operating theatre teams on patient and staff outcomes: a stepped-wedge cluster-randomised trial and mixed-methods study, British Journal of Anaesthesia, In Press 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900230-2/fulltext?dgcid=raven%5Fjbs%5Faip%5Femail).
- PeRiOperative Glucose PRAgmatic (PROGRAM): a randomized trial of standardized insulin management in surgical patients, **Anesthesiology*, 23 May 2025, [Link](https://journals.lww.com/anesthesiology/abstract/9900/perioperative%5Fglucose%5Fpragmatic%5F%5Fprogram%5F%5F%5Fa.689.aspx).
- Self-directed learning versus traditional instructor-led learning for education on a new anaesthesia workstation: a noninferiority, randomised, controlled trial, **British Journal of Anaesthesia*, 23 May 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900276-4/fulltext).
- Comparison between transtracheal and intravenous 2% lignocaine in attenuating hemodynamic stress response following direct laryngoscopy and endotracheal intubation: a randomized controlled trial, **BMC Anesthesiology*, 24 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03102-1).

****Reviews:**

- Hyperangulated videolaryngoscopy, **BJA Education*, June 2025, Review Article, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900023-X/fulltext).
- Pathophysiology and risk factors for postoperative nausea and vomiting in adults and children, **BJA Education*, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900024-1/fulltext).
- Perioperative ventilation support, what clinicians and searchers must know, Anaesthesia Critical Care & Pain Medicine, 22 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000864).
- Sugammadex Anaphylaxis: Mechanisms, Diagnosis, and Incidence, **Anesthesiology*, 20 May 2025, [Link](https://journals.lww.com/anesthesiology/citation/9900/sugammadex%5Fanaphylaxis%5F%5Fmechanisms,%5Fdiagnosis,%5Fand.686.aspx).
- The future of target-controlled infusion and new pharmacokinetic models, **Current Opinion in Anesthesiology*, 26 May 2025, [Link](https://journals.lww.com/co-anesthesiology/fulltext/9900/the%5Ffuture%5Fof%5Ftarget%5Fcontrolled%5Finfusion%5Fand%5Fnew.306.aspx).
- Advancing electroencephalography education in anesthesiology, **Current Opinion in Anesthesiology*, 26 May 2025, [Link](https://journals.lww.com/co-anesthesiology/fulltext/9900/advancing%5Felectroencephalography%5Feducation%5Fin.304.aspx).
- Remimazolam for anesthesia in cardiac and noncardiac surgery. A narrative literature review and synthesis, **Anaesthesia Critical Care & Pain Medicine*, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000876).
1. ****Regional Anesthesia & Pain Medicine:**

****Systematic Reviews & Meta-Analyses:**

- Efficacy of Epidural Analgesia Compared to Intravenous Lidocaine for Postoperative Pain in Major Abdominal Surgery: A Systematic Review and Meta-Analysis, **Current Anesthesiology Reports*, 13 May 2025, [Link](https://link.springer.com/article/10.1007/s40140-025-00699-4).

****Randomized Controlled Trials (RCTs):**

- Intravenous dexmedetomidine as addition to dexamethasone adjunct for interscalene brachial plexus block for postoperative analgesia after arthroscopic shoulder surgery: A randomised, double-blinded, single centre trial, **European Journal of Anaesthesiology*, 14 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/intravenous%5Fdexmedetomidine%5Fas%5Faddition%5Fto.296.aspx).
- Repeat-dose dexamethasone to prevent pain relapse after total knee arthroplasty in high-pain-response patients: A randomised, double-blind, placebo-controlled superiority trial, **European Journal of Anaesthesiology*, 14 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/repeat%5Fdose%5Fdexamethasone%5Fto%5Fprevent%5Fpain%5Frelapse.297.aspx).
- Ultrasound-guided supraclavicular brachial plexus block as an additive to sevoflurane anesthesia in pediatrics undergoing brachiobasilic arteriovenous fistula operation: randomized controlled clinical trial, **BMC Anesthesiology*, 16 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03091-1).
- A novel approach to ultrasound-guided L3-4 thoracolumbar fascia injection for chronic pain after spine surgery: a prospective pilot study, **BMC Anesthesiology*, 15 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03046-6).
- Ultrasound Gel versus Saline for Acoustic Coupling in Ultrasound-Guided Regional Anesthesia: A Randomized, Cross-Over, Simulation Study, **Anesthesia & Analgesia*, 26 May 2025, [Link](https://journals.lww.com/anesthesia-analgesia/fulltext/9900/ultrasound%5Fgel%5Fversus%5Fsaline%5Ffor%5Facoustic%5Fcoupling.1312.aspx).
- A Randomized Clinical Trial of Dexmedetomidine on Delirium, Cognitive Dysfunction, and Sleep After Non-Ambulatory Orthopedic Surgery With Regional Anesthesia, **Anesthesia & Analgesia*, 22 May 2025, [Link](https://journals.lww.com/anesthesia-analgesia/fulltext/9900/a%5Frandomized%5Fclinical%5Ftrial%5Fof%5Fdexmedetomidine%5Fon.1303.aspx).
- Thoracic paravertebral block versus local infiltration anesthesia for percutaneous kyphoplasty to treat osteoporotic vertebral compression fractures combined with intercostal neuralgia: a randomized controlled trial, **BMC Anesthesiology*, 19 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03114-x).
- Double dural puncture epidural improves quality of labour analgesia without increasing adverse effects in primipara: A randomised controlled trial, **European Journal of Anaesthesiology*, 22 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/double%5Fdural%5Fpuncture%5Fepidural%5Fimproves%5Fquality%5Fof.303.aspx).
- Postoperative Analgesia Effect Evaluation of Perineural Dexamethasone Plus Various Doses of Ropivacaine in Interscalene Brachial Plexus Block: A Randomized Controlled Trial, **The Clinical Journal of Pain*, 22 May 2025, [Link](https://journals.lww.com/clinicalpain/fulltext/9900/postoperative%5Fanalgesia%5Feffect%5Fevaluation%5Fof.261.aspx).
- Comparison of analgesic efficacy of erector spinae plane block at different levels in laparoscopic cholecystectomies: a randomized controlled trial, **BMC Anesthesiology*, 26 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03138-3).

****Reviews:**

- Sublingual ketamine for acute postoperative pain: an emerging addition to multimodal analgesia, **British Journal of Anaesthesia*, In Press 2025, [Link](https://click.notification.elsevier.com/CL0/https:%2F%2Fwww.bjanaesthesia.org%2Farticle%2FS0007-0912%2825%2900232-6%2Ffulltext%3Fdgcid=raven%5Fjbs%5Faip%5Femail/1/01000196ddc6b16d-1a8131c5-3691-4f7f-9b71-cf2e1e379ddd-000000/ae3zvrS23gVhaUQ4gjiPLd6mzpjss9G3Od-nHlaRZHw=405).
- Regional anesthesia in bariatric surgery, **Current Opinion in Anesthesiology*, 29 April 2025, [Link](https://journals.lww.com/co-anesthesiology/fulltext/9900/regional%5Fanesthesia%5Fin%5Fbariatric%5Fsurgery.303.aspx) .
1. ****Cardiothoracic Anesthesia:**

****Systematic Reviews & Meta-Analyses:**

- Temporal Trends and Severity of Postoperative Delirium in Cardiac Surgery: Insights from A Systematic Review and Meta-Analysis, **Journal of Cardiothoracic and Vascular Anesthesia*, 17 May 2025, [Link](https://www.jcvaonline.com/article/S1053-0770%2825%2900402-1/abstract).
- The Protective Effect of Remote Ischemic Preconditioning on Acute Kidney Injury Following Pediatric Cardiac Surgery: A Systematic Review and Meta-Analysis, **Journal of Cardiothoracic and Vascular Anesthesia*, 17 may 2025, [Link](https://www.jcvaonline.com/article/S1053-0770%2825%2900403-3/abstract).
- Effect of dexmedetomidine on the incidence of postoperative delirium following major cardiac surgery: An updated meta-analysis, **Journal of Cardiothoracic and Vascular Anesthesia*, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004355).

****Randomized Controlled Trials (RCTs):**

- Effect of Dinalbuphine sebacate on postoperative multimodal analgesic strategy in video-assisted thoracoscopic surgery: a double-blind randomized controlled trial, **BMC Anesthesiology*, 17 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03118-7).
- Methylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial, **Critical Care Medicine*, May 21 2025, [Link](https://journals.lww.com/ccmjournal/fulltext/9900/methylprednisolone%5Ffor%5Finfant%5Fheart%5Fsurgery%5F.527.aspx).
- Comparison between upper body and full underbody forced-air warming blanket in pediatric patients undergoing cardiovascular interventions under general anesthesia: a randomized controlled trial, **BMC Anesthesiology*, 21 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03100-3#).
- Sugammadex or neostigmine for reversal of neuromuscular block on the quality of postoperative recovery in elderly adults undergoing video-assisted thoracoscopic lobectomy: a randomised controlled trial, **BMC Anesthesiology*, 16 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03128-5).

****Reviews:**

- Pharmacokinetics and Pharmacodynamics of Analgesic and Anesthetic Drugs in Patients During Cardiac Surgery With Cardiopulmonary Bypass: A Narrative Review, **Anesthesia & Analgesia*, May 16, 2025, narrative Review, [Link](https://journals.lww.com/anesthesia-analgesia/fulltext/9900/pharmacokinetics%5Fand%5Fpharmacodynamics%5Fof%5Fanalgesic.1299.aspx).
- Right Ventricular Function and Echocardiographic Pressure-Volume Loops; Overview and Perioperative Clinical Implications, Journal of Cardiothoracic and Vascular Anesthesia, 17 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S105307702500401X).
1. ****Neuroanesthesia:**

****Reviews:**

- Anaesthesia for resection of vestibular schwannoma, **BJA Education*, May 14, 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900026-5/fulltext?dgcid=raven%5Fjbs%5Faip%5Femail).
- Anaesthesia for clipping of intracranial aneurysms, **BJA Education*, 24 May 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900038-1/abstract).
1. ****Pediatric Anesthesia:**

****Randomized Controlled Trials (RCTs):**

- Low-dose Esketamine combined with Propofol in microscopic pediatric strabismus surgery: a randomized controlled study, **BMC Anesthesiology*, 14 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03095-x).
- Effects of different doses of remifentanil combined with sevoflurane anesthesia on postoperative analgesia and hemodynamics in pediatric patients undergoing laparoscopic inguinal hernia repair, **BMC Anesthesiology*, 15 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03104-z).

****Reviews:**

- Perioperative management of tracheo-oesophageal fistula and oesophageal atresia, **BJA Education*, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900025-3/fulltext).
1. ****Obstetric Anesthesia:**

****Randomized Controlled Trials (RCTs):**

- Impact of Erythromycin and Metoclopramide on Gastric Emptying of Solids in Term Pregnant Women Scheduled for Elective Cesarean Delivery: A Randomized Controlled Trial, **Anaesthesia Critical Care & Pain Medicine*, 14 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000761?via%3Dihub).
- Interleukin-1 receptor antagonist polymorphisms in women receiving epidural analgesia who develop maternal intrapartum fever: a prospective, multicentre Mendelian randomised study, **British Journal of Anaesthesia*, 14 May 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900226-0/fulltext).
- No effect of tetracosactide for treatment of postdural puncture headaches in parturient women: a double-blind randomised controlled clinical trial, **British Journal of Anaesthesia*, 20 May 2025, [Link](https://www.bjanaesthesia.org/article/S0007-0912%2825%2900233-8/fulltext).
- QUAdratus lumborum block in caesarean section (QUALICS) study: A randomised clinical trial comparing intrathecal morphine, quadratus lumborum block and the combination of both for postoperative analgesia in caesarean sections, **European Journal of Anaesthesiology*, 22 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/quadratus%5Flumborum%5Fblock%5Fin%5Fcaesarean%5Fsection.304.aspx).

****Reviews:**

- Adjuncts for neuraxial anaesthesia in obstetrics, **BJA Education*, June 2025, [Link](https://www.bjaed.org/article/S2058-5349%2825%2900022-8/fulltext).
1. ****Other:**

****Randomized Controlled Trials (RCTs):**

- Effects of an opioid-free care pathway vs. opioid-based standard care on postoperative pain and postoperative quality of recovery after laparoscopic bariatric surgery: A multicentre randomised controlled trial, **European Journal of Anaesthesiology*, 15 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/effects%5Fof%5Fan%5Fopioid%5Ffree%5Fcare%5Fpathway%5Fvs%5F.298.aspx).
- Safety of remimazolam in deep sedation during flexible fiberoptic bronchoscopy: a prospective, randomized controlled trial, **BMC Anesthesiology*, 15 May 2025, [Link](https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03117-8).
- Recovery from deep neuromuscular blockade using different sugammadex doses in elderly patients undergoing laparoscopic robot-assisted prostatectomy: A prospective, randomised, double-blind, phase III trial, **European Journal of Anaesthesiology*, 22 May 2025, [Link](https://journals.lww.com/ejanaesthesiology/fulltext/9900/recovery%5Ffrom%5Fdeep%5Fneuromuscular%5Fblockade%5Fusing.301.aspx).

### 

---

### 

# **Critical Care Highlights**

### 

### **I. Systematic Reviews & Meta-Analyses:**

1. The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis, Critical Care, 12 May 2025, [Link](https://ccforum.biomedcentral.com/articles/10.1186/s13054-025-05402-x).
2. Oxygen and carbon dioxide targets after cardiac arrest: an updated systematic review, Resuscitation, June 2025, [Link](https://www.sciencedirect.com/science/article/pii/S0300957225001327).
3. High flow nasal therapy versus noninvasive ventilation for AECOPD with acute hypercapnic respiratory failure: a meta-analysis of randomized controlled trials, Annals of Intensive Care, 14 May 2025, [Link](https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-025-01480-w).
4. Critical Care Ultrasonography for Volume Management: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomized Trials, Critical Care Explorations, 14 May 2025, [Link](https://journals.lww.com/ccejournal/fulltext/2025/05000/critical%5Fcare%5Fultrasonography%5Ffor%5Fvolume.11.aspx).
5. The diagnostic accuracy of serum procalcitonin for sepsis in adult emergency department patients. A systematic review and meta-analysis, CHEST Critical Care, 22 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900052-8/fulltext).
6. Treatment of agitation in dementia - a systematic review, International Journal of Emergency Medicine, 26 May 2025, [Link](https://intjem.biomedcentral.com/articles/10.1186/s12245-025-00902-7).
7. Comparison of the diagnostic accuracies of various biomarkers and scoring systems for sepsis: A systematic review and Bayesian diagnostic test accuracy network meta-analysis, Journal of critical care, August 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S0883944125000747).
8. Does cardiopulmonary resuscitation before donor death affect solid organ transplant function? A systematic review and *meta*\-analysis, Resuscitation, 21 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S0300957225001662#).
9. Use of CPR feedback devices in resuscitation training: A systematic review and meta-analysis of randomized controlled trials, Resuscitation Plus, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425000761).
10. Manikin physical realism for resuscitation education: A systematic review, Resuscitation Plus, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425000773).
11. Advanced airway interventions for paediatric cardiac arrest: updated systematic review and *meta*\-analysis, Resuscitation Plus, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425001006).
12. Pulse check accuracy in pediatrics during resuscitation: a systematic review, Resuscitation Plus, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425000967).
13. Video vs. traditional laryngoscopy for tracheal intubation at birth or in the neonatal unit: A systematic review and meta-analysis, Resuscitation Plus, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S266652042500102X).
14. Energy doses for paediatric defibrillation in cardiac arrest: systematic review and meta-analysis, Resuscitation Plus, 26 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425001286).
15. Novel biomarkers for predicting successful liberation of renal replacement therapy for acute kidney injury: a systematic review, Critical Care, 26 May 2025, [Link](https://ccforum.biomedcentral.com/articles/10.1186/s13054-025-05451-2).

### **II. Randomized Controlled Trials (RCTs):**

1. Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial, Intensive care medicine, 13 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07910-4).
2. The Significance of Possible Non-Occlusive Mesenteric Ischemia in Relation to Neurological Outcomes in Patients with Refractory Cardiac Arrest - Secondary Analysis of the Prague OHCA Study, Resuscitation, 15 May 2025, [Link](https://www.resuscitationjournal.com/article/S0300-9572%2825%2900154-6/abstract).
3. Immediate or delayed initiation of renal replacement therapy in patients with leptospirosis and acute kidney injury: a target trial emulation, Annals of Intensive Care, 14 May 2025, [Link](https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-025-01477-5).
4. Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill PatientsThe A2B Randomized Clinical Trial, JAMA, 19 may 2025, [Link](https://jamanetwork.com/journals/jama/fullarticle/2834276).
5. Ascorbate for Organ Dysfunction in Critically Ill Patients with Sepsis – The Phase 2b ASTER Trial, Chest critical care, 19 may 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900041-3/fulltext).
6. Protocol and Statistical Analysis Plan for a Multicenter Randomized Trial of Ketamine vs Etomidate for Emergency Tracheal Intubation, CHEST Critical Care, 21 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2949788425000504).
7. Cost-Effectiveness of α2 Agonists for Intravenous Sedation in Patients With Critical Illness, JAMA Network Open, 19 May 2025, [Link](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2834255).
8. ROBotic-assisted Early Mobilization in Ventilated Surgical Critically ill Patients (ROBEM-I) – a randomized, controlled, outcome-assessor-blinded pilot study, Anaesthesia Critical Care & Pain Medicine, 23 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2352556825000815).
9. Protocol and Statistical Analysis Plan for the Vasopressin for Septic Shock Pragmatic (VASSPR) Cluster-Crossover Randomized Trial, CHEST Critical Care, 21 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900051-6/fulltext).
10. Improving Recovery and Outcomes Every Day After the ICU (IMPROVE): A Randomized Controlled Trial, Critical Care Medicine, 22 May 2025, [Link](https://journals.lww.com/ccmjournal/abstract/9900/improving%5Frecovery%5Fand%5Foutcomes%5Fevery%5Fday%5Fafter.530.aspx).
11. Postresuscitation pleth variability index-guided hemodynamic management of out-of-hospital cardiac arrest survivors: A randomised controlled trial, Resuscitation Plus, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425000700).
12. Hydrocortisone and arginine vasopressin in post-resuscitation shock: the HYVAPRESS trial, Resuscitation Plus, 19 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425001195).
13. Temporal stability of inflammatory subphenotypes of acute respiratory distress syndrome: 28-day insights from the ICAR trial, Anaesthesia Critical Care & Pain Medicine, 26 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2352556825000918).
14. Preoxygenation With and Without Positive End-Expiratory Pressure in Lung-Healthy VolunteersA Randomized Clinical Trial, JAMA Network Open, 20 May 2025, [Link](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2834258).

### 

### **III. Reviews**

1. Extracorporeal Membrane Oxygenation In The Awake Or Extubated Patien, Journal of Cardiothoracic and Vascular Anesthesia, 16 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004057).
2. Individualized mean arterial pressure targets in critically ill patients guided by non-invasive cerebral-autoregulation: a scoping review, Critical Care, 16 May 2025, [Link](https://ccforum.biomedcentral.com/articles/10.1186/s13054-025-05432-5).
3. Acute traumatic coagulopathy: what you should know, what is debated and what should come next, Anaesthesia Critical Care & Pain Medicine, 16 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S235255682500075X).
4. Acute kidney injury: when and how to start renal replacement therapy, Intensive care medicine, 19 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07933-x).
5. Nutrition and metabolic control for ICU patients, Intensive care medicine, 19 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07937-7).
6. Understanding and mitigating medication errors associated with patient harm in adult intensive care units: a scoping review, Intensive care medicine, 20 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07938-6).
7. How to approach a patient hospitalized for pneumonia who is not responding to treatment?, Intensive care medicine, 24 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07903-3).
8. Immune Thrombotic Thrombocytopenic Purpura, JAMA, 19 may 2025, [Link](https://jamanetwork.com/journals/jama/article-abstract/2834159).
9. Diagnosing pulmonary embolism during pregnancy: A narrative review, CHEST, 20 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S001236922500649X).
10. Anticoagulation Monitoring during Extracorporeal Membrane Oxygenation: a Narrative Review, Journal of Cardiothoracic and Vascular Anesthesia, 24 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004343).
11. Critical insights for intensivists on Guillain-Barré syndrome, Annals of Intensive Care, 21 May 2025, [Link](https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-025-01464-w).
12. Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies, The Lancet Respiratory Medicine, 20 May 2025, [Link](https://www.thelancet.com/journals/lanres/article/PIIS2213-2600%2825%2900124-9/abstract).
13. Implementing Large Language Models in Critical Care: What is Behind the Delay?, CHEST Critical Care, 24 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900053-X/fulltext).
14. Contemporary Rationale for Delivering Enteral Nutrition in Critically Ill Adults, Critical Care Medicine, 21 May 2025, [Link](https://journals.lww.com/ccmjournal/abstract/9900/contemporary%5Frationale%5Ffor%5Fdelivering%5Fenteral.528.aspx).
15. Pulmonary Embolism: Unanswered Questions and Ongoing Evidence Gaps, Journal of Cardiothoracic and Vascular Anesthesia, 20 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004070)
16. What every intensivist should know about type D hyperlactatemia, *Journal of critical care*, August 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S088394412500036X).
17. ICU-acquired weakness: Critical illness myopathy and polyneuropathy, *Journal of critical care*, August 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S0883944125000619).
18. Optimization of antimicrobial therapy in critically ill patients, What Clinicians and Searchers Must Know, Anaesthesia Critical Care & Pain Medicine, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000931).
19. Optimization of antimicrobial therapy in critically ill patients, What Clinicians and Searchers Must Know, Anaesthesia Critical Care & Pain Medicine, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000931).

### **IV. Case Reports/Series:**

1. Diagnostic challenges in pulmonary lymphomatous spread mimicking ARDS in an AIDS patient: a case report, International Journal of Emergency Medicine, 16 May 2025, [Link](https://intjem.biomedcentral.com/articles/10.1186/s12245-025-00889-1).

### 

---

#### By topic:

1. ****Sepsis & Infectious Diseases:**

****Systematic Reviews & Meta-Analyses:**

- The diagnostic accuracy of serum procalcitonin for sepsis in adult emergency department patients. A systematic review and meta-analysis, **CHEST Critical Care*, 22 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900052-8/fulltext).
- Comparison of the diagnostic accuracies of various biomarkers and scoring systems for sepsis: A systematic review and Bayesian diagnostic test accuracy network meta-analysis, **Journal of critical care*, August 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S0883944125000747).

****Randomized Controlled Trials (RCTs):**

- Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial, **Intensive care medicine*, 13 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07910-4).
- Ascorbate for Organ Dysfunction in Critically Ill Patients with Sepsis – The Phase 2b ASTER Trial, **Chest critical care*, 19 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900041-3/fulltext).
- Protocol and Statistical Analysis Plan for the Vasopressin for Septic Shock Pragmatic (VASSPR) Cluster-Crossover Randomized Trial, **CHEST Critical Care*, 21 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900051-6/fulltext).

****Reviews:**

- How to approach a patient hospitalized for pneumonia who is not responding to treatment?, **Intensive care medicine*, 24 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07903-3).
- Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies, **The Lancet Respiratory Medicine*, May 20, 2025, [Link](https://www.thelancet.com/journals/lanres/article/PIIS2213-2600%2825%2900124-9/abstract).
- Optimization of antimicrobial therapy in critically ill patients, What Clinicians and Searchers Must Know, **Anaesthesia Critical Care & Pain Medicine*, 27 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S2352556825000931).
1. ****Mechanical Ventilation & pulmonary:**

****Systematic Reviews & Meta-Analyses:**

- High flow nasal therapy versus noninvasive ventilation for AECOPD with acute hypercapnic respiratory failure: a meta-analysis of randomized controlled trials, **Annals of Intensive Care*, 14 May 2025, [Link](https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-025-01480-w).

****Randomized Controlled Trials (RCTs):**

- Temporal stability of inflammatory subphenotypes of acute respiratory distress syndrome: 28-day insights from the ICAR trial, **Anaesthesia Critical Care & Pain Medicine*, 26 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2352556825000918).
- Preoxygenation With and Without Positive End-Expiratory Pressure in Lung-Healthy VolunteersA Randomized Clinical Trial, **JAMA Network Open*, 20 May 2025, [Link](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2834258).
- Protocol and Statistical Analysis Plan for a Multicenter Randomized Trial of Ketamine vs Etomidate for Emergency Tracheal Intubation, **CHEST Critical Care*, 21 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2949788425000504).

****Reviews:**

- Extracorporeal Membrane Oxygenation In The Awake Or Extubated Patien, Journal of Cardiothoracic and Vascular Anesthesia, 16 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004057).

****Case Reports/Series:**

- Diagnostic challenges in pulmonary lymphomatous spread mimicking ARDS in an AIDS patient: a case report, **International Journal of Emergency Medicine*, 16 May 2025, [Link](https://intjem.biomedcentral.com/articles/10.1186/s12245-025-00889-1).
1. ****Hemodynamics & Resuscitation:**

****Systematic Reviews & Meta-Analyses:**

- Oxygen and carbon dioxide targets after cardiac arrest: an updated systematic review, **Resuscitation*, June 2025, [Link](https://www.sciencedirect.com/science/article/pii/S0300957225001327).
- Critical Care Ultrasonography for Volume Management: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomized Trials, **Critical Care Explorations*, May 14, 2025, [Link](https://journals.lww.com/ccejournal/fulltext/2025/05000/critical%5Fcare%5Fultrasonography%5Ffor%5Fvolume.11.aspx).
- Does cardiopulmonary resuscitation before donor death affect solid organ transplant function? A systematic review and meta-analysis, Resuscitation, 21 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S0300957225001662#).
- Advanced airway interventions for paediatric cardiac arrest: updated systematic review and meta-analysis, Resuscitation *Plus*, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425001006).
- Pulse check accuracy in pediatrics during resuscitation: a systematic review, Resuscitation *Plus*, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425000967).
- Video vs. traditional laryngoscopy for tracheal intubation at birth or in the neonatal unit: A systematic review and meta-analysis, Resuscitation *Plus*, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S266652042500102X).
- Energy doses for paediatric defibrillation in cardiac arrest: systematic review and meta-analysis, Resuscitation *Plus*, 26 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425001286).

****Randomized Controlled Trials (RCTs):**

- The Significance of Possible Non-Occlusive Mesenteric Ischemia in Relation to Neurological Outcomes in Patients with Refractory Cardiac Arrest - Secondary Analysis of the Prague OHCA Study, **Resuscitation*, 15 May 2025, [Link](https://www.resuscitationjournal.com/article/S0300-9572%2825%2900154-6/abstract).
- Postresuscitation pleth variability index-guided hemodynamic management of out-of-hospital cardiac arrest survivors: A randomised controlled trial, Resuscitation *Plus*, May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425000700).
- Hydrocortisone and arginine vasopressin in post-resuscitation shock: the HYVAPRESS trial, Resuscitation *Plus*, 19 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2666520425001195).

****Reviews:**

- Individualized mean arterial pressure targets in critically ill patients guided by non-invasive cerebral-autoregulation: a scoping review, **Critical Care*, 16 May 2025, [Link](https://ccforum.biomedcentral.com/articles/10.1186/s13054-025-05432-5).
- Acute traumatic coagulopathy: what you should know, what is debated and what should come next, Anaesthesia Critical Care & Pain Medicine, 16 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S235255682500075X).
- Anticoagulation Monitoring during Extracorporeal Membrane Oxygenation: a Narrative Review, Journal of Cardiothoracic and Vascular Anesthesia, 24 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004343).
- Pulmonary Embolism: Unanswered Questions and Ongoing Evidence Gaps, Journal of Cardiothoracic and Vascular Anesthesia, 20 May 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S1053077025004070).
- What every intensivist should know about type D hyperlactatemia, **Journal of critical care*, August 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S088394412500036X).
1. ****Neurocritical Care:**

****Reviews:**

- Critical insights for intensivists on Guillain-Barré syndrome, **Annals of Intensive Care*, 21 May 2025, [Link](https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-025-01464-w).
1. ****Renal & Electrolyte Management:**

****Systematic Reviews & Meta-Analyses:**

- The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis, **Critical Care*, 12 May 2025, [Link](https://ccforum.biomedcentral.com/articles/10.1186/s13054-025-05402-x).
- Novel biomarkers for predicting successful liberation of renal replacement therapy for acute kidney injury: a systematic review, **Critical Care*, 26 May 2025, [Link](https://ccforum.biomedcentral.com/articles/10.1186/s13054-025-05451-2).

****Randomized Controlled Trials (RCTs):**

- Immediate or delayed initiation of renal replacement therapy in patients with leptospirosis and acute kidney injury: a target trial emulation, **Annals of Intensive Care*, 14 May 2025, [Link](https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-025-01477-5).

****Reviews:**

- Acute kidney injury: when and how to start renal replacement therapy, **Intensive care medicine*, 19 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07933-x).
1. ****Nutrition & Metabolism in ICU:**

****Reviews:**

- Nutrition and metabolic control for ICU patients, **Intensive care medicine*, 19 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07937-7).
- Contemporary Rationale for Delivering Enteral Nutrition in Critically Ill Adults, **Critical Care Medicine*, May 21, 2025, [Link](https://journals.lww.com/ccmjournal/abstract/9900/contemporary%5Frationale%5Ffor%5Fdelivering%5Fenteral.528.aspx).
1. ****Sedation and Analgesia:**

****Randomized Controlled Trials (RCTs):**

- Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill PatientsThe A2B Randomized Clinical Trial, **JAMA*, 19 May 2025, [Link](https://jamanetwork.com/journals/jama/fullarticle/2834276).
- Cost-Effectiveness of α2 Agonists for Intravenous Sedation in Patients With Critical Illness, **JAMA Network Open*, 2025, 19 May 2025, [Link](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2834255).
1. ****Other:**

****Randomized Controlled Trials (RCTs):**

- ROBotic-assisted Early Mobilization in Ventilated Surgical Critically ill Patients (ROBEM-I) – a randomized, controlled, outcome-assessor-blinded pilot study, **Anaesthesia Critical Care & Pain Medicine*, 23 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S2352556825000815).
- Improving Recovery and Outcomes Every Day After the ICU (IMPROVE): A Randomized Controlled Trial, **Critical Care Medicine*, May 22, 2025, [Link](https://journals.lww.com/ccmjournal/abstract/9900/improving%5Frecovery%5Fand%5Foutcomes%5Fevery%5Fday%5Fafter.530.aspx).

****Reviews:**

- Understanding and mitigating medication errors associated with patient harm in adult intensive care units: a scoping review, **Intensive care medicine*, 20 May 2025, [Link](https://link.springer.com/article/10.1007/s00134-025-07938-6).
- Immune Thrombotic Thrombocytopenic Purpura, **JAMA*, 19 May 2025, [Link](https://jamanetwork.com/journals/jama/article-abstract/2834159).
- Diagnosing pulmonary embolism during pregnancy: A narrative review, **CHEST*, 20 May 2025, [Link](https://www.sciencedirect.com/science/article/pii/S001236922500649X).
- Implementing Large Language Models in Critical Care: What is Behind the Delay?, **CHEST Critical Care*, 24 May 2025, [Link](https://www.chestcc.org/article/S2949-7884%2825%2900053-X/fulltext).
- ICU-acquired weakness: Critical illness myopathy and polyneuropathy, **Journal of critical care*, August 2025, [Link](https://www.sciencedirect.com/science/article/abs/pii/S0883944125000619).

### 

---

### **Feedback & Suggestions**

Don't hesitate to share your thoughts and suggestions in the comments below; they'll be a great help in improving future issues of the newsletter.

**Disclaimer**

💡

****Disclaimer:**  
The is for educational and informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.

See you next week, Thursday 5th of June 2025 :)

**Benhalima Othmane.**

**Anecrit.com**

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