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This week's highlight: three new AHA scientific statements on perioperative anemia and patient blood management in cardiac surgery, secondary prevention after CABG, and perinatal heart failure. Plus the usual roundup — 36 papers in anaesthesiology, 47 in critical care.

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Anesthesiology:

Guidelines & Consensus:

1- Cardiovascular & Hemodynamics:

1. Perioperative Anemia and Patient Blood Management in Cardiac Surgery: A Scientific Statement From the American Heart Association, Circulation, 22 June 2026, Link
2. Secondary Prevention After Coronary Artery Bypass Graft Surgery: 2026 Update: A Scientific Statement From the American Heart Association, Circulation, 13 May 2026, Link

2- Obstetrics & Gynecology:

3. Heart Failure Occurring in the Perinatal Period: A Scientific Statement From the American Heart Association, Circulation, 24 June 2026, Link

Systematic reviews & meta-analyses:

1- Neuro:

4. Remimazolam Versus Propofol for Anesthesia in Intracranial Neurosurgeries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Journal of Neurosurgical Anesthesiology, 19 June 2026, Link

2- Cardiovascular & Hemodynamics:

5. Machine learning vs. traditional methods for predicting postoperative cardiac complications after non-cardiac surgery: a systematic review and Bayesian network meta-analysis, Anaesthesia, 22 June 2026, Link
6. Hemodynamic effects of dexmedetomidine versus propofol in cardiac surgery: a systematic review and meta-analysis, BMC Anesthesiology, 20 June 2026, Link

3- Regional Anesthesia & Pain Management:

7. Effect of ultrasound-guided fascial plane block (UGPB) on pain control of rib fractures: a systematic review and meta-analysis, BMC Anesthesiology, 24 June 2026, Link
8. Effects of single-injection vs. continuous brachial plexus blocks for shoulder surgeries on patient-reported outcomes: a systematic review and meta-analysis with trial sequential analysis of randomised controlled trials, Anaesthesia, 23 June 2026, Link

Clinical trials:

1- Airway & Mechanical Ventilation:

9. Respiration-Related Catheter Displacement and Physiological Tolerance of High-Frequency Very-Low Tidal Volume Ventilation with Peak Pressure Limitation During Atrial Fibrillation Ablation: A Prospective One-Way Crossover Pilot Study, Journal of Cardiothoracic and Vascular Anesthesia, 24 June 2026, Link
10. Hypotension and pulmonary atelectasis during general anaesthesia: a randomised crossover laboratory study, BJA, 24 June 2026, Link
11. Individualized PEEP titration guided by static lung compliance reduces postoperative atelectasis in elderly patients during laparoscopic Trendelenburg surgery: a randomized controlled trial, Perioperative Medicine, 19 June 2026, Link
12. Stellate ganglion block for attenuating postoperative sore throat after double-lumen tube intubation in thoracic surgery: a randomized clinical study, Perioperative Medicine, 17 June 2026, Link

2- Cardiovascular & Hemodynamics:

13. Effect of the orexin receptor antagonist, suvorexant, on sleep architecture in the early postoperative period following cardiac surgery: a randomized controlled trial, Critical Care, 23 June 2026, Link
14. Perioperative intravenous fluid and chronic kidney disease: long-term follow-up of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery (RELIEF) randomised trial, BJA, 22 June 2026, Link

3- Obstetrics & Gynecology:

15. Low-dose esketamine for postoperative fatigue after gynecological laparoscopic surgery: a randomized controlled trial, BMC Anesthesiology, 26 June 2026, Link
16. Low-dose intrathecal morphine versus intrathecal fentanyl for post-caesarean analgesia in a resource-constrained setting: a pragmatic randomised trial, BMC Anesthesiology, 23 June 2026, Link
17. Remimazolam vs. propofol for prevention of postoperative nausea and vomiting in laparoscopic gynecological surgery: a randomized non-inferiority trial, Perioperative Medicine, 16 June 2026, Link

4- Regional Anesthesia & Pain Management:

18. Self-Directed vs Clinician-Delivered Cognitive Behavioral Therapy for Chronic Pain: A Randomized Clinical Trial, JAMA, 24 June 0226, Link
19. Stellate ganglion block for attenuating postoperative sore throat after double-lumen tube intubation in thoracic surgery: a randomized clinical study, Perioperative Medicine, 17 June 2026, Link

5- Other:

20. Intravenous lidocaine reduces propofol requirements during endoscopic ultrasound: a randomized, double-blinded, controlled trial, BMC Anesthesiology, 22 June 2026, Link

Reviews:

1- Neuro:

21. Central nervous system stimulants: basic pharmacology and relevance to anaesthesia and critical care, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link

2- Cardiovascular & Hemodynamics:

22. Preoperative cardiac optimization, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
23. Noninvasive Arterial Pressure Monitoring during Anesthesia, Anesthesiology, 18 June 2026, Link

3- Regional Anesthesia & Pain Management:

24. Eye-tracking technology applied to regional anaesthesia task performance, safety and skill acquisition: a scoping review, BJA, 25 June 2026, Link
25. Enhanced recovery pathways for patients with chronic pain: beyond standard protocols – a narrative review, Current Opinion in Anesthesiology, 23 June 2026, Link
26. Novel technologies and innovations in postoperative follow-up after regional anesthesia, Current Opinion in Anesthesiology, 19 June 2026, Link

4- Other:

27. Prehabilitation, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
28. Confidentiality: a practical guide for anaesthetic and intensive care medicine practitioners, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
29. Conflict resolution, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
30. Suction devices, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
31. Omics and anaesthesia: pharmacogenomics, proteomics and metabolomics, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
32. Frailty assessment in the pre-operative setting, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
33. Gastric disorders: modifications of gastric content, antacids and drugs influencing gastric secretions and motility, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
34. Clinical aspects of hepatic disease, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
35. Drugs and the liver, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
36. European simulation-based education and training in anaesthesiology and intensive care: evidence, value and inevitable evolution, European Journal of Anaesthesiology, 22 June 2026, Link

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Critical Care:

Guidelines & Consensus:

1- Cardiovascular & Hemodynamics:

1. Heart Failure Occurring in the Perinatal Period: A Scientific Statement From the American Heart Association, Circulation, 24 June 2026, Link
2. Perioperative Anemia and Patient Blood Management in Cardiac Surgery: A Scientific Statement From the American Heart Association, Circulation, 22 June 2026, Link
3. Secondary Prevention After Coronary Artery Bypass Graft Surgery: 2026 Update: A Scientific Statement From the American Heart Association, Circulation, 13 May 2026, Link

Systematic reviews & meta-analyses:

1- Cardiovascular & Hemodynamics:

4. The effectiveness of tissue-perfusion-guided resuscitation in shock: A systematic review and meta-analysis, Annals of Intensive Care, 25 June 2026, Link

2- Neuro-muscular:

5. Ventriculostomy-Related Infections by Country-Income Level: A Systematic Review and Bayesian Hierarchical Meta-analysis, Journal of Neurosurgical Anesthesiology, 15 June 2026, Link
6. Association Between Intracranial Pressure Variability and Clinical Outcomes in Acute Brain Injury: A Systematic Review and Meta-Analysis, Journal of Neurosurgical Anesthesiology, 15 June 2026, Link

3- Trauma:

7. Acute intoxication and trauma severity in emergency department patients: a systematic review, BMC Emergency Medicine, 23 June 2026, Link
8. Clinical outcomes of hemostatic interventions in patients with traumatic injury: A systematic review of randomized controlled trials, The Journal of Trauma and Acute Care Surgery, 15 June 2026, Link

4- Infectious Diseases:

9. Comparative efficacy and safety of extended versus continuous infusion of beta-lactam antibiotics for severe infection: a network meta-analysis of randomized trials, Critical Care, 20 June 2026, Link
10. Diagnostic accuracy of presepsin for sepsis in adult patients according to the criteria of sepsis-3: systematic review and meta-analysis, BMC Anesthesiology, 19 June 2026, Link

Clinical trials:

1- Cardiovascular & Hemodynamics:

11. Effect of the orexin receptor antagonist, suvorexant, on sleep architecture in the early postoperative period following cardiac surgery: a randomized controlled trial, Critical Care, 23 June 2026, Link

2- Thorax/Lungs/Airways/Mechanical ventilation:

12. Standardized low-flow ventilation with PEEP maintenance during bronchoscopy in mechanically ventilated ICU patients: a pilot trial, Journal of Intensive Care, 21 June 2026, Link

3- Neuro-muscular:

13. Safety and Efficacy of Nerinetide at Year 1 in Participants Enrolled in ESCAPE‐NEXT: A Multicenter, Double‐Blind, Randomized Controlled Trial, Journal of the American Heart Association, 23 June 2026, Link
14. CN-105 in Participants with Acute Supratentorial Intracerebral Hemorrhage Trial in Singapore (S-CATCH): A Phase 2b, Randomized, Double-blind, Placebo-Controlled Trial, Neurocritical Care, 23 June 2026, Link
15. Concordance Between Bedside and Electronic Detection of Intracranial Pressure Crises: Insights From the Brain Tissue Oxygen Monitoring and Management in Severe Traumatic Brain Injury II Trial, Critical Care Medicine, 18 June 2026, Link

4- Trauma:

16. Prolonged tourniquet use in extremity trauma: What you need to know, The Journal of Trauma and Acute Care Surgery, 19 June 2026, Link

5- Infectious Diseases:

17. Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial, The Lancet, 17 June 2026, Link

Reviews:

1- Thorax/Lungs/Airways/Mechanical ventilation:

18. PEEP and alveolar recruitment after 60 years of acute respiratory distress syndrome, Intensive Care Medicine, 22 June 2026, Link
19. The role of mechanical power in lung ventilation for the prevention of ventilator-induced lung injury: a narrative review, European Respiratory Review, 29 April 2026, Link

2- Neuro-muscular:

20. Central nervous system stimulants: basic pharmacology and relevance to anaesthesia and critical care, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
21. Beyond the Catheter: Contemporary Aspiration Pump Systems in Neurointerventional Stroke Therapy, Stroke: Vascular and Interventional Neurology, 22 June 2026, Link
22. Emerging Therapy Critique: Glibenclamide for Cerebral Edema—A Semi-CHARMed Treatment, Stroke, 22 June 2026, Link
23. Early Autonomic Dysfunction Following TBI and Possible Interventions: A Narrative Review, Journal of Neurosurgical Anesthesiology, 18 June 2026, Link
24. Immune System of the Ischemic Brain: Old Paradigms Revisited, Stroke, 27 May 2026, Link
25. Taking a Glimpse Into the Brain’s Immune System: Imaging and Blood-Based Biomarkers of the Poststroke Immune Response, Stroke, 27 May 2026, Link
26. Inflammation in Acute Ischemic Stroke: Translational Barriers and Implications for Treatment, Stroke, 27 May 2026, Link
27. Thromboinflammation in Acute Stroke: From Pathophysiological Challenges to Emerging Therapeutic Opportunities, Stroke, 27 May 2026, Link
28. Inflammation in Aneurysmal Subarachnoid Hemorrhage: Cause, Consequence, or Both? Focus on Pathogen Pattern Recognition, Stroke, 27 May 2026, Link
29. Inflammation as a Key Driver for Chronic Subdural Hematomas, Stroke, 27 May 2026, Link

3- Liver & GI:

30. Gastric disorders: modifications of gastric content, antacids and drugs influencing gastric secretions and motility, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
31. Drugs and the liver, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link

4- Blood & hemostasis:

32. Mouse models to study von Willebrand factor in inflammation: a scoping review, Intensive Care Medicine Experimental, 24 June 2026, Link

5- Nutrition:

33. Feeding under support in critical care illness: metabolic and nutritional management during extracorporeal membrane oxygenation and continuous renal replacement therapy, Current Opinion in Critical Care, 22 June 2026, Link

6- Infectious Diseases:

34. Bundibugyo Virus Disease in 2026 — Clinical and Public Health Responses, NEJM, 24 June 2026, Link
35. Systemic corticosteroids for severe community-acquired pneumonia: a narrative review of mechanisms and critical appraisal of recent trials in ICU, European Respiratory Review, 24 June 2026, Link
36. Antimicrobial Resistance in Patients with Sepsis, Critical Care Clinics, 22 June 2026, Link
37. Real-time Subgrouping of Sepsis and Systemic Inflammatory Syndromes, Critical Care Clinics, 22 June 2026, Link
38. Post-Sepsis Syndrome after Critical Illness: Epidemiology and Long-term Outcomes, Critical Care Clinics, 22 June 2026, Link

7- Pediatric critical care:

39. Hypodermoclysis for Fluid Administration in Hospitalized Pediatric Patients: A Scoping Review, Pediatric Emergency Care, 22 June 2026, Link

8- Other:

40. Neurocritical Care Fellowship Training in the USA: Challenges and Potential Solutions, Neurocritical Care, 26 June 2026, Link
41. Consent, Anaesthesia & Intensive Care Medicine, 25 June 2026, Link
42. Immune-Mediated Inflammatory Diseases and the Critically Ill, Critical Care Clinics, 25 June 2026, Link
43. Negligence, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
44. Confidentiality: a practical guide for anaesthetic and intensive care medicine practitioners, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
45. Conflict resolution, Anaesthesia & Intensive Care Medicine, 24 June 2026, Link
46. European simulation-based education and training in anaesthesiology and intensive care: evidence, value and inevitable evolution, European Journal of Anaesthesiology, 22 June 2026, Link
47. Multinational collaborations in critical care research: feasible and useful?, Current Opinion in Critical Care, 22 June 2026, Link

Feedback & Suggestions

Don't hesitate to share your thoughts and suggestions in the comments below; they'll be a great help in improving future issues of the newsletter.

See you next time :)

Benhalima Othmane, MD.

Anecrit.com