Newsletter #30
Get concise anesthesia & Critical Care updates, every week.
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Anesthesiology:
Guidelines & Consensus:
1- AI:
- Responsible use of large language models in manuscript authorship, peer review, and editorial processes: a Delphi consensus among editors-in-chief of anesthesia and pain medicine journals (RULE-AP), BJA, 25 February 2026, Link
2- General:
- Professional practice guidelines: Eco-Responsible Optimization of Choice and use of Drugs and Medical Devices in Operating Theatres or interventional sector, Anaesthesia Critical Care & Pain Medicine, 17 February 2026, Link
3- Thoracic:
- Monitoring in Thoracic Anesthesia: EACTAIC Consensus Document, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
4- Neuro:
- Consensus document on electroencephalography education in anaesthesiology: defining learning outcomes: A modified four-round Delphi study, EJA, 19 February 2026, Link
5- Obstetrics & Gynecology:
- Pain management in childbirth: neuraxial analgesia and drug alternatives, Anesthesia Critical Care & Pain Medicine, 17 February 2026, Link
6- Pediatric:
- Multimodality Approach to Coronary Ischemic Testing in Pediatric Patients: A Scientific Statement From the American Heart Association, JAHA, 26 February 2026, Link
7- Regional Anesthesia & Pain Management:
- Defining the need for analgesia in the emergency department: an international consensus statement, European Journal of Emergency Medicine, 25 February 2026, Link
Systematic reviews & meta-analyses:
1- General:
- A systematic review of efforts to predict day of surgery cancellation, EJA, 25 February 2026, Link
- Antibiotic Prophylaxis Strategies and Surgical Site Infections in Colorectal Surgery: A Systematic Review and Network Meta-Analysis, JAMA Open, 19 February 2026, Link
2- Cardiovascular & Hemodynamics:
- The Effects of Tranexamic Acid on Renal Outcomes in Patients Undergoing Cardiovascular Surgery: A Systematic Review and Meta-Analysis Compliant With Preferred Reporting Items for Systematic Reviews and Meta-Analyses, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Sex-related Incidence of Stroke After Left Ventricular Assist Device Implantation: A Systematic Review and Meta-analysis, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Evaluating Topical Antifibrinolytics in Cardiac Surgery: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Benefits of nitric oxide administration during cardiopulmonary bypass on postoperative outcomes in adult patients: a meta-analysis and systematic review, BMC Anesthesiology, 25 February 2026, Link
- Preoperative and Intraoperative Risk Factors for Postoperative Pneumonia After Cardiac Surgery: An Ancillary Study of the STERNOCAT (Catheter Outcomes With Sternotomy Cardiac Operated) Randomized Trial and a Systematic Review With Meta-Analysis, Critical Care Medicine, 11 February 2026, Link
3- Neuro:
- Psychological factors associated with postoperative cognitive outcomes in older adults: a systematic review and meta-analysis, BJA, 27 February 2026, Link
- Impaired Cognitive Domains in Surgical Patients: A Systematic Review and Meta-Analysis, A&A, 16 February 2026, Link
4- Obstetrics & Gynecology:
- The impact of neuraxial labour analgesia on neurodevelopmental disorders in offspring: a systematic review and meta-analysis, BJA, 3 March 2026, Link
5- Pediatric:
- Effectiveness of parental presence during induction of anaesthesia in managing perioperative anxiety in children: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials, BMC Anesthesiology, 23 February 2026, Link
- Early Versus Late Extubation After Pediatric Cardiac Surgery: A Systematic Review and Meta-analysis, Journal of Cardiothoracic and Vascular Anesthesia, 19 February 2026, Link
6- Regional Anesthesia & Pain Management:
- The effect of adding a second multimodal analgesic component to anesthesia regimens on acute postoperative pain outcomes: a systematic review and meta-analysis, BMC Anesthesiology, 4 March 2026, Link
Get concise anesthesia & Critical Care updates, every week.
Join the growing community of anesthesiologists and intensivists staying current on the latest evidence.
Clinical trials:
1- General:
- Intranasal low-dose dexmedetomidine alleviates propofol-associated postoperative sleep disturbance in female hysteroscopy patients: a randomized controlled trial, BMC Anesthesiology, 27 February 2026, Link
- Ciprofol versus propofol and the risk of hemodynamic adverse events: a meta-analysis with trial sequential analysis of randomized controlled trials, BMC Anesthesiology, 27 February 2026, Link
- Dexmedetomidine reduces pulmonary complications in older patients undergoing abdominal laparoscopic surgery: a prospective, single-blinded, randomized controlled trial, BMC Anesthesiology, 14 February 2026, Link
2- Airway & Mechanical Ventilation:
- Combination of COMBO endoscopy oropharyngeal airway and high-flow nasal cannula oxygenation in sedated gastrointestinal endoscopy for morbidly obese patients: a Simon two-stage trial, BMC Anesthesiology, 19 February 2026, Link
3- Cardiovascular & Hemodynamics:
- Effect of Subcutaneous vs Topical nitroglycerin on the radial artery dimensions in pediatric patients undergoing surgery: A randomized non-inferiority trial, Journal of Cardiothoracic and Vascular Anesthesia, 4 March 2026, Link
- Perioperative Multimodal General Anesthesia Focusing on Specific Central Nervous System Targets Does Not Reduce Postoperative Interleukin-6 and Neurofilament Light Levels in Patients Undergoing Cardiac Surgeries: A Randomized Controlled Trial, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
4- Thoracic:
- Effects of preconditioning with one-lung ventilation on perioperative oxygenation and oxidative stress in thoracoscopic surgery: a prospective single-center randomized controlled clinical trial, BMC Anesthesiology, 28 February 2026, Link
- Right lateral decubitus as a strategy to improve left bronchial blocker placement in thoracic operations: a randomized clinical trial, BMC Anesthesiology, 23 February 2026, Link
- Effect of oliceridine versus morphine on the quality of early recovery after thoracoscopic surgery: a randomized, controlled clinical trial, BMC Anesthesiology, 13 February 2026, Link
5- Obstetrics & Gynecology:
- The 90% effective dose (ED90) of esketamine for inhibiting responses to intraoperative motor stimulation during ambulatory hysteroscopy: a biased-coin up-and-down sequential allocation trial, BMC Anesthesiology, 14 February 2026, Link
6- Pediatric:
- The effect of preoperative remimazolam application on emergence delirium in children under sevoflurane anesthesia based on electroencephalogram analysis: a randomized, double-blind, placebo-controlled study, BMC Anesthesiology, 5 March 2026, Link
- Clinical effectiveness of transversus abdominis plane block versus local anaesthesia wound infiltration for postoperative pain relief after laparoscopic appendicectomy in children: A multicentre, double-blind, randomised, controlled phase III trial, EJA, 4 March 2026, Link
- A novel dexmedetomidine nasal spray for gastrointestinal recovery in pediatric laparoscopic hernia repair: a randomized controlled trial, BMC Anesthesiology, 18 February 2026, Link
- Effectiveness of McGRATH MAC Video Laryngoscopy for First-Attempt Intubation by Anesthesia Trainees in Infants: A Randomized Controlled Trial, A&A, 16 February 2026, Link
- Lung Ultrasound Evaluation of the Impact of Inspired Oxygen Fraction on Atelectasis During Induction of General Anesthesia in Pediatric Patients: A Randomized Controlled Trial, Shock, 31 December 2025, Link
7- Orthopedic:
- Impact of a thermal care bundle on perioperative hypothermia, surgical site infection, and readmissions in osteosynthesis patients: A randomized controlled trial, EJA, 17 February 2026, Link
8- Regional Anesthesia & Pain Management:
- Modified longitudinal intermediate cervical plexus block for supraclavicular nerve analgesia: a randomized, double-blind trial in healthy volunteers, BMC Anesthesiology, 28 February 2026, Link
- Respiratory effects of rectus sheath block in patients undergoing major upper abdominal surgery: a randomized controlled trial, BMC Anesthesiology, 26 February 2026, Link
- Morphine Plus Placebo vs Morphine Plus Acetaminophen for Acute Pain in the Emergency Department: A Randomized Clinical Trial, JAMA Open, 24 February 2026, Link
- Quadratus lumborum block versus femoral nerve block in total hip arthroplasty: a randomized clinical trial, BMC Anesthesiology, 24 February 2026, Link
- Ultrasound-guided retro-superior costotransverse ligament space block (RSSB) versus subcostal transversus abdominis plane block (TAPB) for postoperative analgesia in gastric cancer patients undergoing laparoscopic gastrectomy : a prospective randomized controlled trial, BMC Anesthesiology, 23 February 2026, Link
- Impact of preoperative continuous supra-inguinal fascia iliaca block or anterior quadratus lumborum block versus conventional analgesia on quality of recovery after hip fracture surgery: a three-arm randomized clinical trial, BMC Anesthesiology, 23 February 2026, Link
- Application of anterior sciatic nerve block with liposomal bupivacaine in lower leg fracture surgery: a randomized clinical trial, BMC Anesthesiology, 23 February 2026, Link
- CYP2D6-Guided Opioid Management and Postoperative Pain Control: A Randomized Clinical Trial, JAMA Open, 20 February 2026, Link
- Reduced movement-evoked pain with liposomal bupivacaine versus ropivacaine in transversus abdominis plane block for laparoscopic colorectal surgery: a randomized controlled trial, BMC Anesthesiology, 17 February 2026, Link
- Comparison of sympathetic block and hemodynamic effects of erector spinae plane block and thoracic epidural analgesia in breast surgery: a randomised controlled trial, BMC Anesthesiology, 14 February 2026, Link
Reviews:
1- AI:
- Machine learning for hemodynamic instability prediction and hemorrhage management in trauma and perioperative care, Current Opinion in Anesthesiology, April 2026, Link
- Real-time, artificial intelligence–guided intraoperative resuscitation and fluid management in trauma anesthesia, Current Opinion in Anesthesiology, April 2026, Link
- Data integration and systems interoperability: the prerequisite for artificial intelligence in anesthesiology, Current Opinion in Anesthesiology, April 2026, Link
- Artificial intelligence and predictive analytics in obstetric anesthesia: early warning for maternal complications, Current Opinion in Anesthesiology, 11 February 2026, Link
2- General:
- Perioperative Acute Kidney Injury: What’s New in 2025?, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Optimizing Perioperative Management of Sarcoidosis in Noncardiac Surgery: A Focused Review and Practical Framework, Anesthesiology, 17 February 2026, Link
3- Cardiovascular & Hemodynamics:
- The Year in Coagulation and Transfusion: Selected Highlights, Journal of Cardiothoracic and Vascular Anesthesia, 4 March 2026, Link
- Advances in Cardiovascular Pharmacotherapy. VI. Sacubitril-Valsartan, An Angiotensin Receptor-Neprilysin Inhibitor, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Respiratory Reactivation of Herpes Simplex Virus-1 Following Cardiac Surgery in Immunocompetent Individuals, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Management of Liver Cirrhosis in Percutaneous and Surgical Cardiac Interventions, JAHA, 24 February 2026, Link
- Intraoperative blood pressure management in noncardiac surgery: a narrative review based on current evidence, Intensive Care Medicine, 17 February 2026, Link
4- Thoracic:
- Perioperative Anesthetic Management of Giant Mediastinal Tumours: Current Advances and Evidence-Based Strategies, Journal of Cardiothoracic and Vascular Anesthesia, 20 February 2026, Link
5- Neuro:
- Timing of Surgery After Ischemic Stroke, Journal of Neurosurgical Anesthesiology, April 2026, Link
6- Regional Anesthesia & Pain Management:
- Suzetrigine, a novel nonopioid analgesic for acute pain, Current Opinion in Anesthesiology, 17 February 2026, Link
- Pain management of adults in the prehospital setting: a scoping review, BMC Emergency Medicine, 17 February 2026, Link
- Common interventional techniques for cancer-related pain, BJA Edu, 13 February 2026, Link
Critical Care:
Guidelines & Consensus:
1- Cardiovascular & Hemodynamics:
- 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines, Circulation, 19 February 2026, Link
- 2026 Acute Pulmonary Embolism Guideline-at-a-Glance, JACC, 23 February 2026, Link
2- Trauma:
- Western Trauma Association critical decisions in trauma: Significant blunt cardiac injury, Journal of Trauma and Acute Care Surgery, 20 February 2026, Link
- Executive summary of the Brain Trauma Foundation Guidelines for the Management of Penetrating Traumatic Brain Injury, Second Edition, Journal of Trauma and Acute Care Surgery, March 2026, Link
3- Blood & hemostasis:
- An American College of Surgeons Committee on Trauma Stop the Bleed guideline on the use of improvised tourniquets for trauma patients with life-threatening extremity hemorrhage 2025, Journal of Trauma and Acute Care Surgery, 20 February 2026, Link
4- Nutrition:
- Correction: The Japanese Critical Care Nutrition Guideline 2024, Journal of Intensive Care, 28 February 2026, Link
Systematic reviews & meta-analyses:
1- AI:
- Evaluating the impact of artificial intelligence tools on the detection of chest injuries from medical imaging: A systematic review and meta-analysis, Journal of Trauma and Acute Care Surgery, 12 February 2026, Link
2- Cardiovascular & Hemodynamics:
- Prevalence and outcomes of in-hospital cardiac arrest in the intensive care unit: a systematic review and meta-analysis, Critical Care, 27 February 2026, Link
- Intraosseous and intravenous vascular access during adult cardiac arrest: a systematic review and meta-analysis, Resuscitation, 26 February 2026, Link
- The Use of Extracorporeal Membrane Oxygenation in Traumatic Brain Injury and Neurosurgical Patients: A Single-Center Analysis and Systematic Review, Neurocritical Care, 26 February 2026, Link
- Percutaneous Mechanical Aspiration for Tricuspid Valve Infective Endocarditis: A Systematic Review and Meta-Analysis, Journal of Cardiothoracic and Vascular Anesthesia, 13 February 2026, Link
3- Thorax/Lungs/Airways/Mechanical ventilation:
- Effect of driving pressure-limiting strategies on outcomes of patients with ARDS: a meta-analysis of randomized controlled trials, Critical Care, 5 March 2026, Link
4- Trauma:
- Comparative efficacy of prehospital resuscitation strategies on mortality for patients with major trauma: a network meta-analysis, European Journal of Emergency Medicine, 9 February 2026, Link
5- Infectious Diseases:
- Venoarterial Extracorporeal MembraneOxygenation in Septic Shock and/or Sepsis-induced Cardiomyopathy: A Systematic Review of Fifteen Studies, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Prognostic Factors Associated with Pneumonia in Patients with Traumatic Brain Injury: A Systematic Review and Meta-analysis, Neurocritical Care, 26 February 2026, Link
- Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections: A Systematic Review and Meta-Analysis, JAMA Open, 12 February 2026, Link
6- Other:
- Effects of digital communication tools on patients, family members and health care professionals in adult ICUs: a mixed-methods systematic review, Critical Care, 3 March 2026, Link
Clinical trials:
1- Cardiovascular & Hemodynamics:
- Low-Dose Rivaroxaban to Prevent Left Ventricular Thrombosis After Anterior Myocardial Infarction: The APERITIF Randomized Clinical Trial, JAM, 25 February 2026, Link
- The effect of plasma versus crystalloids on intravascular volume, tissue perfusion and tissue oxygenation: a randomized controlled trial in a human endotoxemia model, Critical CXare, 24 February 2026, Link
- Evaluating hands-free carotid Doppler ultrasound for real-time return of spontaneous circulation detection in in-hospital cardiac arrest: a multicenter randomized controlled study, Resuscitation, 18 February 2026, Link
- Comparison of the European Society of Cardiology 0/1-Hour and High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome 0/2-or-0/3-Hour Algorithms for Rapid Myocardial Infarction Diagnosis: A Prospective Multicenter Study, JACC, 18 February 2026, Link
2- Thorax/Lungs/Airways/Mechanical ventilation:
- Blade Size and Outcomes with Standard-Geometry Video Laryngoscopy in Emergency Tracheal Intubations: Secondary Analysis of Two Randomized Controlled Trials, CHEST Critical Care, 5 March 2026, Link
- Fiberoptic Bronchoscopy Monitoring During Percutaneous Dilatational Tracheostomy: A Multicenter, Randomized, Controlled Trial. The FIBERTRACH Randomized Clinical Trial, Critical Care Medicine, 26 February 2026, Link
- Comparison of two different recruitment maneuver patterns in ARDS patients, Intensive Care Medicine Experimental, 14 February 2026, Link
3- Neuro-muscular:
- Head Down Position Before Endovascular Treatment for Large Vessel Occlusion: Clinical Trial Design, JAHA, 4 March 2026, Link
- Feasibility of Calculating and Maintaining Near-Infrared Spectroscopy-Guided Personalized Mean Arterial Pressure Targets in Adults With Critical Illness: A Pilot Clinical Study, Critical Care Explorations, March 2026, Link
- Critical illness–related corticosteroid insufficiency after acute brain hemorrhage surgery: a prospective cohort study with a randomized trial of hydrocortisone, Critical Care, 24 February 2026, Link
- Safety and Efficacy of Early Aspirin Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND‐IVT): Rationale and Design of a Multicenter, Randomized, Placebo‐Controlled Clinical Trial, JAHA, 20 February 2026, Link
4- Renal:
- Prognosis of critically ill patients with severe acute kidney injury and high circulating dipeptidyl peptidase 3: a post hoc analysis of the AKIKI 2 trial, 3 March 2026, Link
- Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial, BJA, 24 February 2026, Link
5- Trauma:
- Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial, Intensive Care Medicine, 3 March 2026, Link
6- Nutrition:
- The Impact of Early Enteral Nutrition on Ventilator- and Vasopressor-Free Days in Mechanically Ventilated Patients with Septic Shock: A Secondary Analysis of a Pilot Randomized Controlled Trial, CHEST Critical Care, 26 February 2026, Link
7- Infectious Diseases:
- Albumin Replacement Therapy in Septic Shock: A Randomized Clinical Trial, JAMA Open, 19 February 2026, Link
- Effect of Neostigmine on Attenuation of Proinflammatory Cytokines When Given as an Adjuvant Therapy in Septic Shock: A Randomized Controlled Trial, Critical Care Medicine, 12 February 2026, Link
- Clinical and Immunologic Effects of Extracorporeal Cytokine Removal in Patients with Septic Shock: A Randomized Controlled Trial, Shock, 4 February 2026, Link
8- Sedation & analgesia:
- Eyecontrol coMmunication platform for dEliRium manaGemEnt in intensive care units (EMERGE): Protocol for a Multicentre Randomized Controlled Trial, CHEST Critical Care, 26 February 2026, Link
- Association between ABCDE bundle compliance and long-term outcomes: a secondary longitudinal analysis, Intensive Care Medicine, 25 February 2026, Link
9- Pediatric critical care:
- Protocol for a Randomized Clinical Trial to Evaluate Not Routinely Measuring Gastric Residual Volume to Guide Enteral Feeding Versus Routine Measurement in Mechanically Ventilated Critically Ill Children (GASTRIC-PICU), Pediatric Critical Care Medicine, 26 February 2026, Link
Reviews:
1- Cardiovascular & Hemodynamics:
- Advances in cardiovascular pharmacotherapy. VII. Soluble guanylate cyclase stimulators in pulmonary hypertension and heart failure, Journal of Cardiothoracic and Vascular Anesthesia, 25 February 2026, Link
- Extracorporeal cardiopulmonary resuscitation in adult patients following in-hospital and out-of-hospital refractory cardiac arrest: A Narrative Review, Journal of Cardiothoracic and Vascular Anesthesia, 24 February 2026, Link
- Prehospital diagnosis and management of supraventricular tachycardia – a scoping review, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 21 February 2026, Link
- Revisiting Commotio Cordis: Novel Insight Into Clinical Variability, Diagnosis, Epidemiology, and Prevention, JAHA, 20 February 2026, Link
- Left Ventricular Outflow Tract Obstruction in Critically Ill Patients: from Pathophysiology and diagnosis to the management with the “LVOTO” Bundle, Anaesthesia Critical Care & Pain Medicine, 17 February 2026, Link
- Cardiogenic Shock Detection Using Electronic Medical Records: A Review and Blueprint for Clinical Implementation and Future Research, JAHA, 11 February 2026, Link
2- Thorax/Lungs/Airways/Mechanical ventilation:
- Prediction of high-flow nasal cannula failure in critically ill patients: a narrative review, Journal of Intensive Care, 3 March 2026, Link
- Sex-specific considerations for mechanical ventilation in acute respiratory distress syndrome: implications for female patients in the intensive care unit, a narrative review, BJA, 24 February 2026, Link
- The ISHLT Consensus Statement on the Perioperative Use of ECLS in Lung Transplantation: Highlights and Perioperative Implications, Journal of Cardiothoracic and Vascular Anesthesia, 18 February 2026, Link
3- Neuro-muscular:
- Diagnosis of death using neurological criteria in adults, BJA Edu, 4 March 2026, Link
- Neuroprognostication in Extracorporeal Membrane Oxygenation Patients After Cardiac Arrest: A Narrative Review, Journal of Cardiothoracic and Vascular Anesthesia, March 2026, Link
- Posterior reversible encephalopathy syndrome (PRES): A narrative review of pathophysiology, clinical insights, and advances in management, International Journal of Emergency Medicine, 19 February 2026, Link
4- Renal:
- Mitigating Risk of Kidney Dysfunction After Heart Transplantation and Therapeutic Approaches, Circulation: Heart Failure, 23 February 2026, Link
- Urinary oxygen partial pressure as a potential biomarker for acute kidney injury: a narrative review, Shock, 23 December 2025, Link
5- Trauma:
- Emergency care for avalanche-buried patients - a narrative review, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 20 February 2026, Link
6- Blood & hemostasis:
- Recognizing and Managing Hemophagocytic Lymphohistiocytosis in Adults in the Intensive Care Unit, Critical Care Clinics, 18 February 2026, Link
7- Nutrition:
- Preexisting malnutrition in the ICU, Current Opinion in Critical Care, April 2026, Link
- Macronutrient excess in critical illness: too much of a good thing?, Current Opinion in Critical Care, April 2026, Link
- Advances and Challenges in Sepsis Care in Low-Resource Settings, Critical Care Clinics, 6 March 2026, Link
- The poikilothermic hypothesis of sepsis, Critical Care, 5 March 2026, Link
- Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association, Circulation, 24 February 2026, Link
8- Infectious Diseases:
- Immunocompromised host pneumonia: a shifting landscape of risk, Current Opinion in Pulmonary Medicine, 4 March 2026, Link
9- Pediatric critical care:
- Analgesia and sedation in mechanically ventilated critically ill children, BJA Edu, 25 February 2026, Link
Feedback & Suggestions
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Disclaimer
The is for educational and informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.
See you next time :)
Benhalima Othmane.
Anecrit.com