Issue #[00] | [13 - 28/05/2025]

Welcome!

Hey there! Welcome to the very first issue of Anecrit's newsletter.

Can you guess how many papers were published across relevant journals in anesthesiology and critical care medicine recently? Try, over 400 papers! That's an insane amount of literature for any clinician trying to stay updated, right? I think this newsletter solves a problem we all share: too little time.

This inaugural issue isn't perfect, and it might not cover every relevant paper you'd hoped for. But please remember, this is our newsletter. It will change and evolve over time to become a resource for all of us. So, please don't hesitate to share your feedback and suggestions. We're building this together!

Featured Articles :

Have you read the OPTPRESS trial?

Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial, Intensive care medicine, 13 May 2025, Link

I'll be publishing a summary and an analysis of this trial tomorrow, stay tuned for it.

Anesthesiology Highlights

I. Guidelines & Consensus Statements :

1. Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement, British Journal of Anaesthesia, In Press 2025, Link.

II. Systematic Reviews & Meta-Analyses :

2. Efficacy of Epidural Analgesia Compared to Intravenous Lidocaine for Postoperative Pain in Major Abdominal Surgery: A Systematic Review and Meta-Analysis, Current Anesthesiology Reports, 13 May 2025, Link.
3. Temporal Trends and Severity of Postoperative Delirium in Cardiac Surgery: Insights from A Systematic Review and Meta-Analysis, Journal of Cardiothoracic and Vascular Anesthesia, 17 May 2025, Link.
4. The Protective Effect of Remote Ischemic Preconditioning on Acute Kidney Injury Following Pediatric Cardiac Surgery: A Systematic Review and Meta-Analysis, Journal of Cardiothoracic and Vascular Anesthesia, 17 may 2025, Link
5. Effect of dexmedetomidine on the incidence of postoperative delirium following major cardiac surgery: An updated meta-analysis, Journal of Cardiothoracic and Vascular Anesthesia, 27 May 2025, Link.

III .Randomized Controlled Trials (RCTs) :

6. Intravenous dexmedetomidine as addition to dexamethasone adjunct for interscalene brachial plexus block for postoperative analgesia after arthroscopic shoulder surgery: A randomised, double-blinded, single centre trial, European Journal of Anaesthesiology, May 14 2025, Link.
7. Impact of Erythromycin and Metoclopramide on Gastric Emptying of Solids in Term Pregnant Women Scheduled for Elective Cesarean Delivery: A Randomized Controlled Trial, Anaesthesia Critical Care & Pain Medicine, 14 May 2025, Link.
8. Repeat-dose dexamethasone to prevent pain relapse after total knee arthroplasty in high-pain-response patients: A randomised, double-blind, placebo-controlled superiority trial, European Journal of Anaesthesiology, May 14 2025, Link.
9. Multimodal prehabilitation before lung resection surgery: a multicentre randomised controlled trial, British Journal of Anaesthesia, 2025, Link.
10. Effect of Dinalbuphine sebacate on postoperative multimodal analgesic strategy in video-assisted thoracoscopic surgery: a double-blind randomized controlled trial, BMC Anesthesiology, 17 May 2025, Link.
11. Interleukin-1 receptor antagonist polymorphisms in women receiving epidural analgesia who develop maternal intrapartum fever: a prospective, multicentre Mendelian randomised study, British Journal of Anaesthesia, 14 May 2025, Link.
12. Low-dose Esketamine combined with Propofol in microscopic pediatric strabismus surgery: a randomized controlled study, BMC Anesthesiology, 14 May 2025, Link.
13. Effects of an opioid-free care pathway vs. opioid-based standard care on postoperative pain and postoperative quality of recovery after laparoscopic bariatric surgery: A multicentre randomised controlled trial, European Journal of Anaesthesiology, May 15 2025, Link.
14. Safety of remimazolam in deep sedation during flexible fiberoptic bronchoscopy: a prospective, randomized controlled trial, BMC Anesthesiology, 15 May 2025, Link.
15. Effects of a national team training intervention for operating theatre teams on patient and staff outcomes: a stepped-wedge cluster-randomised trial and mixed-methods study, British Journal of Anaesthesia, In Press 2025, Link.
16. Ultrasound-guided supraclavicular brachial plexus block as an additive to sevoflurane anesthesia in pediatrics undergoing brachiobasilic arteriovenous fistula operation: randomized controlled clinical trial, BMC Anesthesiology, 16 May 2025, Link.
17. Sugammadex or neostigmine for reversal of neuromuscular block on the quality of postoperative recovery in elderly adults undergoing video-assisted thoracoscopic lobectomy: a randomised controlled trial, BMC Anesthesiology, 16 May 2025, Link.
18. Effects of different doses of remifentanil combined with sevoflurane anesthesia on postoperative analgesia and hemodynamics in pediatric patients undergoing laparoscopic inguinal hernia repair, BMC Anesthesiology, 15 May 2025, Link.
19. A novel approach to ultrasound-guided L3-4 thoracolumbar fascia injection for chronic pain after spine surgery: a prospective pilot study, BMC Anesthesiology, 15 May 2025, Link.
20. Methylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial, Critical Care Medicine, May 21 2025, Link.
21. Ultrasound Gel versus Saline for Acoustic Coupling in Ultrasound-Guided Regional Anesthesia: A Randomized, Cross-Over, Simulation Study, Anesthesia & Analgesia, May 26, 2025, Link.
22. A Randomized Clinical Trial of Dexmedetomidine on Delirium, Cognitive Dysfunction, and Sleep After Non-Ambulatory Orthopedic Surgery With Regional Anesthesia, Anesthesia & Analgesia, May 22, 2025, Link.
23. Thoracic paravertebral block versus local infiltration anesthesia for percutaneous kyphoplasty to treat osteoporotic vertebral compression fractures combined with intercostal neuralgia: a randomized controlled trial, BMC Anesthesiology, 19 May 2025, Link.
24. Chewing gum on postoperative oral Malodor in patients undergoing general anesthesia: a randomized non-inferiority trial, BMC Anesthesiology, 21 May 2025, Link.
25. Comparison between upper body and full underbody forced-air warming blanket in pediatric patients undergoing cardiovascular interventions under general anesthesia: a randomized controlled trial, BMC Anesthesiology, 21 May 2025, Link.
26. No effect of tetracosactide for treatment of postdural puncture headaches in parturient women: a double-blind randomised controlled clinical trial, British Journal of Anaesthesia, 20 May 2025, Link.
27. PeRiOperative Glucose PRAgMatic (PROGRAM): a randomized trial of standardized insulin management in surgical patients, Anesthesiology, 23 May 2025, Link.
28. Self-directed learning versus traditional instructor-led learning for education on a new anaesthesia workstation: a noninferiority, randomised, controlled trial, British Journal of Anaesthesia, 23 May 2025, Link.
29. Double dural puncture epidural improves quality of labour analgesia without increasing adverse effects in primipara: A randomised controlled trial, European Journal of Anaesthesiology, 22 May 2025, Link.
30. QUAdratus lumborum block in caesarean section (QUALICS) study: A randomised clinical trial comparing intrathecal morphine, quadratus lumborum block and the combination of both for postoperative analgesia in caesarean sections, European Journal of Anaesthesiology, 22 May 2025, Link.
31. Recovery from deep neuromuscular blockade using different sugammadex doses in elderly patients undergoing laparoscopic robot-assisted prostatectomy: A prospective, randomised, double-blind, phase III trial, European Journal of Anaesthesiology, 22 May 2025, Link.
32. Postoperative Analgesia Effect Evaluation of Perineural Dexamethasone Plus Various Doses of Ropivacaine in Interscalene Brachial Plexus Block: A Randomized Controlled Trial, The Clinical Journal of Pain, 22 May 2025, Link.
33. Comparison between transtracheal and intravenous 2% lignocaine in attenuating hemodynamic stress response following direct laryngoscopy and endotracheal intubation: a randomized controlled trial, BMC Anesthesiology, 24 May 2025, Link.
34. Comparison of analgesic efficacy of erector spinae plane block at different levels in laparoscopic cholecystectomies: a randomized controlled trial, BMC Anesthesiology, 26 May 2025, Link .

IV. Reviews:

35. Pharmacokinetics and Pharmacodynamics of Analgesic and Anesthetic Drugs in Patients During Cardiac Surgery With Cardiopulmonary Bypass: A Narrative Review, Anesthesia & Analgesia, 16 May 2025, Link.
36. Anaesthesia for resection of vestibular schwannoma, BJA Education, May 14, 2025, Link.
37. Hyperangulated videolaryngoscopy, BJA Education, June 2025, Link.
38. Adjuncts for neuraxial anaesthesia in obstetrics, BJA Education, June 2025, Link.
39. Perioperative management of tracheo-oesophageal fistula and oesophageal atresia, BJA Education, June 2025, Link.
40. Pathophysiology and risk factors for postoperative nausea and vomiting in adults and children, BJA Education, June 2025, Link.
41. Sublingual ketamine for acute postoperative pain: an emerging addition to multimodal analgesia, British Journal of Anaesthesia, In Press 2025, Link.
42. Right Ventricular Function and Echocardiographic Pressure-Volume Loops; Overview and Perioperative Clinical Implications, Journal of Cardiothoracic and Vascular Anesthesia, 17 May 2025, Link.
43. Perioperative ventilation support, what clinicians and searchers must know, Anaesthesia Critical Care & Pain Medicine, 22 May 2025, Link.
44. Sugammadex Anaphylaxis: Mechanisms, Diagnosis, and Incidence, Anesthesiology, 20 May 2025, Link.
45. Anaesthesia for clipping of intracranial aneurysms, BJA Education, 24 May 2025, Link.
46. Regional anesthesia in bariatric surgery, Current Opinion in Anesthesiology, 29 April 2025, Link.
47. The future of target-controlled infusion and new pharmacokinetic models, Current Opinion in Anesthesiology, 26 May 2025, Link.
48. Advancing electroencephalography education in anesthesiology, Current Opinion in Anesthesiology, 26 May 2025, Link.
49. Remimazolam for anesthesia in cardiac and noncardiac surgery. A narrative literature review and synthesis, Anaesthesia Critical Care & Pain Medicine, 27 May 2025, Link.

By topic:

Critical Care Highlights

I. Systematic Reviews & Meta-Analyses:

1. The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis, Critical Care, 12 May 2025, Link.
2. Oxygen and carbon dioxide targets after cardiac arrest: an updated systematic review, Resuscitation, June 2025, Link.
3. High flow nasal therapy versus noninvasive ventilation for AECOPD with acute hypercapnic respiratory failure: a meta-analysis of randomized controlled trials, Annals of Intensive Care, 14 May 2025, Link.
4. Critical Care Ultrasonography for Volume Management: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomized Trials, Critical Care Explorations, 14 May 2025, Link.
5. The diagnostic accuracy of serum procalcitonin for sepsis in adult emergency department patients. A systematic review and meta-analysis, CHEST Critical Care, 22 May 2025, Link.
6. Treatment of agitation in dementia - a systematic review, International Journal of Emergency Medicine, 26 May 2025, Link.
7. Comparison of the diagnostic accuracies of various biomarkers and scoring systems for sepsis: A systematic review and Bayesian diagnostic test accuracy network meta-analysis, Journal of critical care, August 2025, Link.
8. Does cardiopulmonary resuscitation before donor death affect solid organ transplant function? A systematic review and meta-analysis, Resuscitation, 21 May 2025, Link.
9. Use of CPR feedback devices in resuscitation training: A systematic review and meta-analysis of randomized controlled trials, Resuscitation Plus, May 2025, Link.
10. Manikin physical realism for resuscitation education: A systematic review, Resuscitation Plus, May 2025, Link.
11. Advanced airway interventions for paediatric cardiac arrest: updated systematic review and meta-analysis, Resuscitation Plus, May 2025, Link.
12. Pulse check accuracy in pediatrics during resuscitation: a systematic review, Resuscitation Plus, May 2025, Link.
13. Video vs. traditional laryngoscopy for tracheal intubation at birth or in the neonatal unit: A systematic review and meta-analysis, Resuscitation Plus, May 2025, Link.
14. Energy doses for paediatric defibrillation in cardiac arrest: systematic review and meta-analysis, Resuscitation Plus, 26 May 2025, Link.
15. Novel biomarkers for predicting successful liberation of renal replacement therapy for acute kidney injury: a systematic review, Critical Care, 26 May 2025, Link.

II. Randomized Controlled Trials (RCTs):

16. Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial, Intensive care medicine, 13 May 2025, Link.
17. The Significance of Possible Non-Occlusive Mesenteric Ischemia in Relation to Neurological Outcomes in Patients with Refractory Cardiac Arrest - Secondary Analysis of the Prague OHCA Study, Resuscitation, 15 May 2025, Link.
18. Immediate or delayed initiation of renal replacement therapy in patients with leptospirosis and acute kidney injury: a target trial emulation, Annals of Intensive Care, 14 May 2025, Link.
19. Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill PatientsThe A2B Randomized Clinical Trial, JAMA, 19 may 2025, Link.
20. Ascorbate for Organ Dysfunction in Critically Ill Patients with Sepsis – The Phase 2b ASTER Trial, Chest critical care, 19 may 2025, Link.
21. Protocol and Statistical Analysis Plan for a Multicenter Randomized Trial of Ketamine vs Etomidate for Emergency Tracheal Intubation, CHEST Critical Care, 21 May 2025, Link.
22. Cost-Effectiveness of α2 Agonists for Intravenous Sedation in Patients With Critical Illness, JAMA Network Open, 19 May 2025, Link.
23. ROBotic-assisted Early Mobilization in Ventilated Surgical Critically ill Patients (ROBEM-I) – a randomized, controlled, outcome-assessor-blinded pilot study, Anaesthesia Critical Care & Pain Medicine, 23 May 2025, Link.
24. Protocol and Statistical Analysis Plan for the Vasopressin for Septic Shock Pragmatic (VASSPR) Cluster-Crossover Randomized Trial, CHEST Critical Care, 21 May 2025, Link.
25. Improving Recovery and Outcomes Every Day After the ICU (IMPROVE): A Randomized Controlled Trial, Critical Care Medicine, 22 May 2025, Link.
26. Postresuscitation pleth variability index-guided hemodynamic management of out-of-hospital cardiac arrest survivors: A randomised controlled trial, Resuscitation Plus, May 2025, Link.
27. Hydrocortisone and arginine vasopressin in post-resuscitation shock: the HYVAPRESS trial, Resuscitation Plus, 19 May 2025, Link.
28. Temporal stability of inflammatory subphenotypes of acute respiratory distress syndrome: 28-day insights from the ICAR trial, Anaesthesia Critical Care & Pain Medicine, 26 May 2025, Link.
29. Preoxygenation With and Without Positive End-Expiratory Pressure in Lung-Healthy VolunteersA Randomized Clinical Trial, JAMA Network Open, 20 May 2025, Link.

III. Reviews

30. Extracorporeal Membrane Oxygenation In The Awake Or Extubated Patien, Journal of Cardiothoracic and Vascular Anesthesia, 16 May 2025, Link.
31. Individualized mean arterial pressure targets in critically ill patients guided by non-invasive cerebral-autoregulation: a scoping review, Critical Care, 16 May 2025, Link.
32. Acute traumatic coagulopathy: what you should know, what is debated and what should come next, Anaesthesia Critical Care & Pain Medicine, 16 May 2025, Link.
33. Acute kidney injury: when and how to start renal replacement therapy, Intensive care medicine, 19 May 2025, Link.
34. Nutrition and metabolic control for ICU patients, Intensive care medicine, 19 May 2025, Link.
35. Understanding and mitigating medication errors associated with patient harm in adult intensive care units: a scoping review, Intensive care medicine, 20 May 2025, Link.
36. How to approach a patient hospitalized for pneumonia who is not responding to treatment?, Intensive care medicine, 24 May 2025, Link.
37. Immune Thrombotic Thrombocytopenic Purpura, JAMA, 19 may 2025, Link.
38. Diagnosing pulmonary embolism during pregnancy: A narrative review, CHEST, 20 May 2025, Link.
39. Anticoagulation Monitoring during Extracorporeal Membrane Oxygenation: a Narrative Review, Journal of Cardiothoracic and Vascular Anesthesia, 24 May 2025, Link.
40. Critical insights for intensivists on Guillain-Barré syndrome, Annals of Intensive Care, 21 May 2025, Link.
41. Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies, The Lancet Respiratory Medicine, 20 May 2025, Link.
42. Implementing Large Language Models in Critical Care: What is Behind the Delay?, CHEST Critical Care, 24 May 2025, Link.
43. Contemporary Rationale for Delivering Enteral Nutrition in Critically Ill Adults, Critical Care Medicine, 21 May 2025, Link.
44. Pulmonary Embolism: Unanswered Questions and Ongoing Evidence Gaps, Journal of Cardiothoracic and Vascular Anesthesia, 20 May 2025, Link
45. What every intensivist should know about type D hyperlactatemia, Journal of critical care, August 2025, Link.
46. ICU-acquired weakness: Critical illness myopathy and polyneuropathy, Journal of critical care, August 2025, Link.
47. Optimization of antimicrobial therapy in critically ill patients, What Clinicians and Searchers Must Know, Anaesthesia Critical Care & Pain Medicine, 27 May 2025, Link.
48. Optimization of antimicrobial therapy in critically ill patients, What Clinicians and Searchers Must Know, Anaesthesia Critical Care & Pain Medicine, 27 May 2025, Link.

IV. Case Reports/Series:

49. Diagnostic challenges in pulmonary lymphomatous spread mimicking ARDS in an AIDS patient: a case report, International Journal of Emergency Medicine, 16 May 2025, Link.

Feedback & Suggestions

Don't hesitate to share your thoughts and suggestions in the comments below; they'll be a great help in improving future issues of the newsletter.

Disclaimer

See you next week, Thursday 5th of June 2025 :)

Benhalima Othmane.

Anecrit.com